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Crestor During Pregnancy and Breastfeeding Crestor should not be taken during pregnancy or during breastfeeding because of potential birth defects Do not take Crestor if you are pregnant or think you may be pregnant, or are planning to become pregnant. Do not use Crestor if you are breastfeeding Birth control pills, also called oral contraceptives, are medications you take by mouth to prevent pregnancy. It is used to prevent pregnancy and works by suppressing ovulation Birth control performs three primary functions to treat PCOS: 1. Absent, missed, or irregular menstrual cycles. Use effective birth control while taking this medicine. Rosuvastatin may pass into breast milk and could harm a nursing baby Crestor may interact with birth control pills, cimetidine, blood thinners, spironolactone, niacin, or other "statin" medications. 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